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Title: Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Authors: Bridger, JM
Arican-Goktas, HD
Jobling, S
Issue Date: 2017
Publisher: Nature Publishing Group
Citation: Nature Communications, 8: pp. 1-11, (2017)
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
ISSN: 2041-1723
Appears in Collections:Dept of Life Sciences Research Papers

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