Please use this identifier to cite or link to this item:
Title: Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Authors: Bridger, JM
Arican-Goktas, HD
Jobling, S
Adema, CM
Hillier, LW
Jones, CS
Loker, ES
Knight, M
Minx, P
Oliveira, G
Raghavan, N
Shedlock, A
Rodrigues do Amaral, L
Assis, JG
Keywords: DNA sequencing;Genome;Genome informatics;Zoology
Issue Date: 16-May-2017
Publisher: Nature Publishing Group
Citation: Adema, C., Hillier, L., Jones, C. et al. Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nat Commun 8, 15451 (2017).
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
ISSN: 2041-1723
Appears in Collections:Dept of Life Sciences Research Papers

Files in This Item:
File Description SizeFormat 
FullText.pdf1.36 MBAdobe PDFView/Open

Items in BURA are protected by copyright, with all rights reserved, unless otherwise indicated.