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http://bura.brunel.ac.uk/handle/2438/15317| Title: | Coloured Petri nets for multi-level, multiscale, and multi-dimensional modelling of biological systems |
| Authors: | Heiner, M Gilbert, D |
| Keywords: | multi-level;multiscale and multidimensional;coloured Petri nets;biological systems |
| Issue Date: | 3-Nov-2017 |
| Citation: | Liu, F., Heiner, M. and Gilbert, D. (2019) 'Coloured Petri nets for multilevel, multiscale and multidimensional modelling of biological systems', Briefings in Bioinformatics, 20 (3), pp. 877 - 886. doi: 10.1093/bib/bbx150. |
| Abstract: | Owing to the availability of data of one biological phenomenon at different levels/scales, modelling of biological systems is moving from single level/scale to multiple levels/scales, which introduces a number of challenges. Coloured Petri nets (ColPNs) have been successfully applied to multilevel, multiscale and multidimensional modelling of some biological systems, addressing many of these challenges. In this article, we first review the basics of ColPNs and some popular extensions, and then their applications for multilevel, multiscale and multidimensional modelling of biological systems. This understanding of how to use ColPNs for modelling biological systems will assist readers in selecting appropriate ColPN classes for specific modelling circumstances. |
| URI: | https://bura.brunel.ac.uk/handle/2438/15317 |
| DOI: | https://doi.org/10.1093/bib/bbx150 |
| ISSN: | 1467-5463 |
| Appears in Collections: | Dept of Life Sciences Research Papers |
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| Fulltext.pdf | Copyright © The Authors 2017. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com | 291.93 kB | Adobe PDF | View/Open |
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