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Title: | Prevalence of swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19: The PHOSP-COVID analysis |
Authors: | Dawson, C Clunie, G Evison, F Duncan, S Whitney, J Houchen-Wolloff, L Bolton, CE Leavy, OC Richardson, M Omer, E McAuley, H Shikotra, A Singapuri, A Sereno, M Saunders, RM Harris, VC Greening, NJ Nolan, CM Wootton, DG Daynes, E Donaldson, G Sargent, J Scott, J Pimm, J Bishop, L McNarry, M Hart, N Evans, RA Singh, S Yates, T Chalder, T Man, W Harrison, E Docherty, A Lone, NI Quint, JK Chalmers, J Ho, LP Horsley, AR Marks, M Poinasamy, K Raman, B Wain, LV Brightling, C Sharma, N Coffey, M Kulkarni, A Wallace, S |
Keywords: | COVID-19;b |
Issue Date: | 26-Jul-2023 |
Publisher: | BMJ Publishing Group on behalf of British Thoracic Society |
Citation: | Dawson, C. et al. (2023) 'Prevalence of swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19: The PHOSP-COVID analysis', BMJ Open Respiratory Research, 2023, 10 (1), pp. 1 - 17. doi: 10.1136/bmjresp-2023-001647. |
Abstract: | Copyright © Author(s) (or their employer(s)) 2023. Objective Identify prevalence of self-reported swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19. Design Multicentre prospective observational cohort study using questionnaire data at visit 1 (2-7 months post discharge) and visit 2 (10-14 months post discharge) from hospitalised patients in the UK. Lasso logistic regression analysis was undertaken to identify associations. Setting 64 UK acute hospital Trusts. Participants Adults aged >18 years, discharged from an admissions unit or ward at a UK hospital with COVID-19. Main outcome measures Self-reported swallow, communication, voice and cognitive compromise. Results Compromised swallowing post intensive care unit (post-ICU) admission was reported in 20% (188/955); 60% with swallow problems received invasive mechanical ventilation and were more likely to have undergone proning (p=0.039). Voice problems were reported in 34% (319/946) post-ICU admission who were more likely to have received invasive (p<0.001) or non-invasive ventilation (p=0.001) and to have been proned (p<0.001). Communication compromise was reported in 23% (527/2275) univariable analysis identified associations with younger age (p<0.001), female sex (p<0.001), social deprivation (p<0.001) and being a healthcare worker (p=0.010). Cognitive issues were reported by 70% (1598/2275), consistent at both visits, at visit 1 respondents were more likely to have higher baseline comorbidities and at visit 2 were associated with greater social deprivation (p<0.001). Conclusion Swallow, communication, voice and cognitive problems were prevalent post hospitalisation for COVID-19, alongside whole system compromise including reduced mobility and overall health scores. Research and testing of rehabilitation interventions are required at pace to explore these issues. |
Description: | Data availability statement:
All data relevant to the study are included in the article or uploaded as supplementary information. Supplementary Data are available online at https://bmjopenrespres.bmj.com/highwire/filestream/141491/field_highwire_adjunct_files/0/bmjresp-2023-001647supp001_data_supplement.pdf . |
URI: | https://bura.brunel.ac.uk/handle/2438/27065 |
DOI: | https://doi.org/10.1136/bmjresp-2023-001647 |
Other Identifiers: | ORCID iDs: Camilla Dawson https://orcid.org/0000-0002-9910-666X; Felicity Evison https://orcid.org/0000-0002-9378-7548; Charlotte E. Bolton https://orcid.org/0000-0002-9578-2249; Olivia C. Leavy https://orcid.org/0000-0002-1503-5535; Neil J. Greening https://orcid.org/0000-0003-0453-7529; Claire Marie Nolan https://orcid.org/0000-0001-9067-599X; Rachael A. Evans https://orcid.org/0000-0002-1667-868X; Nazir I. Lone https://orcid.org/0000-0003-2707-2779; Alex Robert Horsley https://orcid.org/0000-0003-1828-0058; Chris Brightling https://orcid.org/0000-0002-5803-5121. e001647 |
Appears in Collections: | Dept of Health Sciences Research Papers |
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