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Title: | Comorbid health conditions and their impact on social isolation, loneliness, quality of life, and well-being in people with dementia: longitudinal findings from the IDEAL programme |
Authors: | Sabatini, S Martyr, A Hunt, A Gamble, LD Matthews, FE Thom, JM Jones, RW Allan, L Knapp, M Victor, C Pentecost, C Rusted, JM Morris, RG Clare, L |
Keywords: | physical health;comorbidity;illnesses;social network;Alzheimer’s disease |
Issue Date: | 5-Jan-2024 |
Publisher: | BioMed Central (part of Springer Nature) |
Citation: | Sabatini, S. et al. (2023) 'Comorbid health conditions and their impact on social isolation, loneliness, quality of life, and well-being in people with dementia: longitudinal findings from the IDEAL programme', BMC Geriatrics, 2024, 24 (1), 23, pp. 1 - 11. doi: 10.1186/s12877-023-04601-x. |
Abstract: | Copyright . Background: Most people with dementia have multiple health conditions. This study explores (1) number and type of health condition(s) in people with dementia overall and in relation to age, sex, dementia type, and cognition; (2) change in number of health conditions over two years; and (3) whether over time the number of health conditions at baseline is related to social isolation, loneliness, quality of life, and/or well-being. Methods: Longitudinal data from the IDEAL (Improving the experience of Dementia and Enhancing Active Life) cohort were used. Participants comprised people with dementia (n = 1490) living in the community (at baseline) in Great Britain. Health conditions using the Charlson Comorbidity Index, cognition, social isolation, loneliness, quality of life, and well-being were assessed over two years. Mixed effects modelling was used. Results: On average participants had 1.8 health conditions at baseline, excluding dementia; increasing to 2.5 conditions over two years. Those with vascular dementia or mixed (Alzheimer’s and vascular) dementia had more health conditions than those with Alzheimer’s disease. People aged ≥ 80 had more health conditions than those aged < 65 years. At baseline having more health conditions was associated with increased loneliness, poorer quality of life, and poorer well-being, but was either minimally or not associated with cognition, sex, and social isolation. Number of health conditions had either minimal or no influence on these variables over time. Conclusions: People with dementia in IDEAL generally had multiple health conditions and those with more health conditions were lonelier, had poorer quality of life, and poorer well-being. |
Description: | Availability of data and materials:
IDEAL data were deposited with the UK Data Archive in April 2020. Details of how to access the data can be found here: https://reshare.ukdataservice.ac.uk/854293/. Supplementary Information is available online at: https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-023-04601-x#Sec13 . |
URI: | https://bura.brunel.ac.uk/handle/2438/28010 |
DOI: | https://doi.org/10.1186/s12877-023-04601-x |
Other Identifiers: | ORCID iD: Serena Sabatini https://orcid.org/0000-0002-3618-6949 ORCID iD: Anthony Martyr https://orcid.org/0000-0002-1702-8902 ORCID iD: Anna Hunt https://orcid.org/0000-0001-7523-1792 ORCID iD: Laura D. Gamble https://orcid.org/0000-0001-8496-9705 ORCID iD: Fiona E. Matthews https://orcid.org/0000-0002-1728-2388 ORCID iD: Jeanette M. Thom https://orcid.org/0000-0002-6575-3711 ORCID iD: Roy W. Jones https://orcid.org/0000-0002-7953-5985 ORCID iD: Louise Allan https://orcid.org/0000-0002-8912-4901 ORCID iD: Martin Knapp https://orcid.org/0000-0003-1427-0215 ORCID iD: Christina Victor https://orcid.org/0000-0002-4213-3974 ORCID iD: Claire Pentecost https://orcid.org/0000-0003-2048-5538 ORCID iD: Jennifer M. Rusted https://orcid.org/0000-0002-1341-6334 ORCID iD: Robin G. Morris https://orcid.org/0000-0001-7767-5258 ORCID iD: Linda Clare https://orcid.org/0000-0003-3989-5318 |
Appears in Collections: | Dept of Health Sciences Research Papers |
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