Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/32370
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dc.contributor.authorCooper, DL-
dc.contributor.authorWarland, A-
dc.contributor.authorNorris, E-
dc.contributor.authorKilbride, C-
dc.contributor.authorPaddison, S-
dc.contributor.authorBailey, DP-
dc.date.accessioned2025-11-18T18:03:00Z-
dc.date.available2025-11-18T18:03:00Z-
dc.date.issued2025-11-26-
dc.identifierORCiD: Daniel L. Cooper https://orcid.org/0000-0002-8755-3489-
dc.identifierORCiD: Alyson Warland https://orcid.org/0000-0002-4629-0395-
dc.identifierORCiD: Emma Norris https://orcid.org/0000-0002-9957-4025-
dc.identifierORCiD: Cherry Kilbride https://orcid.org/0000-0002-2045-1883-
dc.identifierORCiD: Sue Paddison https://orcid.org/0009-0005-0895-9480-
dc.identifierORCiD: Daniel P. Bailey https://orcid.org/0000-0003-3772-630X-
dc.identifier.citationCooper, D.L. et al. (2025) 'Effects of interventions on sedentary behaviour and cardiovascular disease biomarkers in individuals with spinal cord injury: a systematic review', Disability and Rehabilitation, 0 (ahead of print), pp. 1 - 24. doi: 10.1080/09638288.2025.2592500.en_US
dc.identifier.issn0963-8288-
dc.identifier.urihttps://bura.brunel.ac.uk/handle/2438/32370-
dc.descriptionData availability statement: All data associated with this review can be found within the included published articles.en_US
dc.descriptionSupplemental material:is available online at: https://www.tandfonline.com/doi/full/10.1080/09638288.2025.2592500# .-
dc.descriptionA preprint version of the article is available on Open Science Framework (OSF) at: https://osf.io/5dwm6_v1/ under a Creative Commons Attribution 4.0 International Public License. It has not been certified by peer review.-
dc.description.abstractPurpose: Reducing sedentary behaviour may be an intervention target to improve cardiovascular health in individuals with spinal cord injury. The aim of this study was to systematically review the effects of interventions on sedentary behaviour and cardiovascular disease biomarkers in individuals with paraplegia. Materials and methods: Following prospective protocol registration (CRD42023420260), eleven sources were searched to identify articles, which were screened by two reviewers. Eligible articles included participants with paraplegia, interventions targeting physical activity and/or sedentary behaviour and studies that measured sedentary behaviour and cardiovascular disease biomarkers. Quality of evidence was assessed for each outcome. Results: Two interventions targeting sedentary behaviour and six targeting physical activity were included. One intervention targeting sedentary behaviour and one targeting physical activity reduced sedentary behaviour. Two interventions targeting sedentary behaviour and three targeting physical activity improved cardiovascular disease biomarkers. Quality of evidence was very low for sedentary behaviour and moderate for cardiovascular disease biomarker outcomes. Conclusions: Sedentary behaviour was not improved by physical activity interventions but these interventions may improve cardiovascular disease biomarkers in individuals with paraplegia. Interventions targeting sedentary behaviour, although limited, show potential effectiveness for improving cardiovascular disease biomarkers; such interventions require further investigation to inform public health and clinical care guidelines. IMPLICATIONS FOR REHABILITATION: • Physical activity interventions are not effective for reducing sedentary behaviour in individuals with paraplegia • Evidence regarding interventions targeting sedentary behaviour is limited, but such interventions show some potential effectiveness • Interventions targeting sedentary behaviour in paraplegia should be investigated further to inform their relevance for rehabilitationen_US
dc.description.sponsorshipThe author(s) reported there is no funding associated with the work featured in this article.en_US
dc.format.extent1 - 24-
dc.format.mediumPrint-Electronic-
dc.language.isoenen_US
dc.publisherTaylor and Francisen_US
dc.rightsCreative Commons Attribution 4.0 International-
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subjectcardiometabolic healthen_US
dc.subjectcardiovascular diseaseen_US
dc.subjectspinal cord injuryen_US
dc.subjectparaplegiaen_US
dc.subjectsedentary behaviouren_US
dc.subjectphysical activity.en_US
dc.titleEffects of interventions on sedentary behaviour and cardiovascular disease biomarkers in individuals with spinal cord injury: a systematic reviewen_US
dc.typeArticleen_US
dc.date.dateAccepted2025-11-16-
dc.identifier.doihttps://doi.org/10.1080/09638288.2025.2592500-
dc.relation.isPartOfDisability and Rehabilitation-
pubs.issue0-
pubs.publication-statusPublished online-
pubs.volume00-
dc.identifier.eissn1464-5165-
dc.rights.licensehttps://creativecommons.org/licenses/by/4.0/legalcode.en-
dcterms.dateAccepted2025-11-16-
dc.rights.holderThe Author(s)-
Appears in Collections:Dept of Life Sciences Research Papers
Dept of Health Sciences Research Papers

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