Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/32594
Title: Holistic Care Clinic for People with Parkinson’s Disease: Outcome from a Newly Developed Service
Authors: Ricciardi, L
Ishihara, B
González-Herrero, B
Pradhan, P
Leake, A
Trinchillo, A
Bernardo, M
Kerogoi, L
Gallogly, P
Paviour, D
Makovac, E
Morgante, F
Keywords: Parkinson’s disease;anxiety;non-motor symptoms;holistic care;wellness
Issue Date: 29-Dec-2025
Publisher: MDPI
Citation: Ricciardi, L. et al. (2026) 'Holistic Care Clinic for People with Parkinson’s Disease: Outcome from a Newly Developed Service', Brain Sciences, 16 (1), 43, pp. 1 - 12. doi: 10.3390/brainsci16010043.
Abstract: Background/Objectives: Non-motor symptoms (NMS) in Parkinson’s disease (PD), particularly neuropsychiatric disturbances such as anxiety, significantly impact quality of life. The Holistic Care Clinic for Parkinson’s disease at St George’s Hospital offers multidisciplinary assessments and personalized care to address both motor and non-motor symptoms, aiming to improve patient well-being and empower patients to manage their health and enhance their quality of life. This study evaluated the effectiveness of a holistic management approach for PD patients with prominent non-motor symptoms, particularly neuropsychiatric issues, by analyzing clinical outcomes and patient feedback. Methods: A retrospective analysis was conducted on patients referred to the clinic between June 2022 and June 2023 for non-motor symptoms. Patients received comprehensive assessments, including clinical exams and interviews focused on neuropsychiatric symptoms, followed by individualized care plans. Interventions for anxiety included online psychoeducation and cardiac biofeedback. Outcomes were assessed using the Clinical Global Impression (CGI) scale and patient feedback on interventions. Results: Thirty patients (mean age 65.7 years, mean disease duration 7.8 years) were included. Anxiety was the primary referral reason (66%). CGI scores indicated that 62% of patients experienced improvement. Medications were adjusted in 14 patients and 65% improved. For anxiety, 13 patients attended the psychoeducation session, with 91% rating it “very likely”/”likely” to recommend. Ten patients completed cardiac biofeedback training, showing a significant reduction in Parkinson’s Anxiety Scale scores (p = 0.03), and 90% recommending it. Conclusions: The holistic care approach of PD patients resulted in significant improvements in clinical outcomes. Patient feedback indicates high satisfaction with the interventions, supporting their acceptability and overall satisfaction with the interventions.
Description: Data Availability Statement: The data presented in this study are available on request from the corresponding author due to ethical restrictions.
Supplementary Materials: The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/brainsci16010043/s1. Table S1: Sustainability and Reproducibility Measures of the Holistic Care Clinic Model.
URI: https://bura.brunel.ac.uk/handle/2438/32594
DOI: https://doi.org/10.3390/brainsci16010043
Other Identifiers: ORCiD: Assunta Trinchillo https://orcid.org/0000-0002-9413-3394
ORCiD: Elena Makovac https://orcid.org/0000-0002-7018-1906
Article number: 43
Appears in Collections:Dept of Life Sciences Research Papers

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