H-SynEx: Using synthetic images and ultra-high resolution ex vivo MRI for hypothalamus subregion segmentation See

The hypothalamus is a small structure located in the center of the brain and is involved in significant functions such as sleeping, temperature, and appetite control. Various neurological disorders are also associated with hypothalamic abnormalities. Automated image analysis of this structure...

Thalamus involvement in genetic frontotemporal dementia assessed using structural and diffusion MRI: a GENFI study See

Thalamic subregions are commonly, but variably, affected by different forms of frontotemporal dementia. We aimed to better characterize thalamic subregional involvement in genetic frontotemporal dementia with a recently published thalamus segmentation tool that utilizes structural and diffusion MRI, offeri...

Impaired glymphatic system in genetic frontotemporal dementia: a GENFI study See

The glymphatic system is an emerging target in neurodegenerative disorders. Here, we investigated the activity of the glymphatic system in genetic frontotemporal dementia with a diffusion-based technique called diffusion tensor image analysis along the perivascular space. We investigated 291 subjects&...

Concurrent validity, test–retest reliability, and normative properties of the ignite app: A cognitive assessment for frontotemporal dementia. See

Objective: Digital biomarkers can provide frequent, real-time monitoring of health-related behavior and could play an important role in the assessment of cognition in frontotemporal dementia (FTD). However, the validity and reliability of digital biomarkers as measures of cognitive function must ...

Neuroanatomical normative modelling in frontotemporal lobar degeneration: higher heterogeneity in the behavioural variant See

Introduction: Frontotemporal lobar degeneration (FTLD) includes heterogenous diseases: behavioural variant frontotemporal dementia (bvFTD), primary progressive aphasias (PPA), progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). We applied neuroanatomical normative modelling to quantify individual atro...

New calculus rules of relative subdifferentials and applications to constrained optimization problems See

This paper investigates properties and calculus rules, including new calculation formulas of chain rules and maximum-pointwise rules for the relative subdifferentials of nondifferentiable functions. Based on these properties and calculation rules, we establish novel optimality conditions without normal con...

Information Theoretic Learning for Diffusion Models with Warm Start See

Generative models that maximize model likelihood have gained traction in many practical settings. Among them, perturbation-based approaches underpin many state-of-the-art likelihood estimation models, yet they often face slow convergence and limited theoretical understanding. In this paper, we derive a...

Three-Dimensional Finite Element Modeling of Drilling-Induced Damage in S2/FM94 Glass-Fiber-Reinforced Polymers (GFRPs) See

Considering that the machining of composites particularly fiber-reinforced polymer composites (FRPCs) has remained a challenge associated with their heterogeneity and anisotropic nature, damage caused by drilling operations can be considerably mitigated by following optimum cutting parameters. In this work...

Effects of interventions on sedentary behaviour and cardiovascular disease biomarkers in individuals with spinal cord injury: a systematic review See

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