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http://bura.brunel.ac.uk/handle/2438/24149
Title: | The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19 |
Authors: | Triay, R Buchhanolla, P Gaudet, A Winter, V Gaudet, A Riel-Romero, RMS Javalkar, V Kelley, RE Ansari, J Faraji, M Gonzalez-Toledo, E Cuellar-Saenz, HH Bailey, S Siddaiah, H Gavins, FNE |
Keywords: | COVID-19;cerebrovascular disease;acute ischemic stroke;seizures;stroke |
Issue Date: | 13-Feb-2022 |
Publisher: | MDPI AG |
Citation: | Triay, R., Buchhanolla, P., Gaudet, A., Winter, V., Gaudet, A., Riel-Romero, R.M.S., Javalkar, V., Kelley, R.E., Ansari, J., Faraji, M., Gonzalez-Toledo, E., Cuellar-Saenz, H.H., Bailey, S., Siddaiah, H. and Gavins, F.N.E. (2022) ‘The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19’, Biomedicines, 10 (2), 435, pp. 1-12. doi: 10.3390/biomedicines10020435. |
Abstract: | Copyright: © 2022 by the authors. (1) Background: COVID-19 infection is responsible for the ongoing pandemic and acute cerebrovascular disease (CVD) has been observed in COVID-19 patients. (2) Methods: We conducted a retrospective, observational study of hospitalized adult patients admitted to our hospital with SARS-CoV-2 and acute cerebrovascular disease. All clinical data were reviewed including epidemiology, clinical features, laboratory data, neuroradiological findings, hospital management and course from 32 patients hospitalized for COVID-19 management with acute cerebrovascular disease. (3) Results: Acute CVD with COVID-19 was associated with higher NIH stroke scale on discharge compared to non-COVID-19 CVDs. Seizures complicated the hospital course in 16% of COVID-19 patients with CVD. The majority of the acute CVDs were ischemic (81%) in nature followed by hemorrhagic (22%). Acute CVD with COVID-19 resulted in average hospital stays greater than twice that of the control group (13 days in COVID-19, 5 days in control). Acute CVD with COVID-19 patients had worse clinical outcomes with 31% patient deaths and 6% discharged to hospice. In the control group, 6% of patients died. (4) Conclusions: Acute CVD associated with COVID-19 tends to be more complicated with unique and adverse clinical phenotype, longer hospital admissions, and worse clinical outcomes. |
URI: | https://bura.brunel.ac.uk/handle/2438/24149 |
DOI: | https://doi.org/10.3390/biomedicines10020435 |
Other Identifiers: | 435 |
Appears in Collections: | Dept of Life Sciences Research Papers |
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