Brunel University Research Archive(BURA) preserves and enables easy and open access to all
types of digital content. It showcases Brunel's research outputs.
Research contained within BURA is open access, although some publications may be subject
to publisher imposed embargoes. All awarded PhD theses are also archived on BURA.
Please use this identifier to cite or link to this item:
http://bura.brunel.ac.uk/handle/2438/29417| Title: | The emerging role of cell surface receptor and protein binding radiopharmaceuticals in cancer diagnostics and therapy |
| Authors: | Aloj, L Attili, B Lau, D Caraco, C Lechermann, LM Mendichovszky, IA Harper, I Cheow, H Casey, RT Sala, E Gilbert, FJ Gallagher, FA |
| Keywords: | receptors;cell membrane proteins;positron emission tomography;targeted radionuclide therapy;radiopharmaceutical development |
| Issue Date: | 12-Jun-2020 |
| Publisher: | Elsevier |
| Citation: | Aloj, L. et al. (2021) 'The emerging role of cell surface receptor and protein binding radiopharmaceuticals in cancer diagnostics and therapy', Nuclear Medicine and Biology, 92, pp. 53 - 64. doi: 10.1016/j.nucmedbio.2020.06.005. |
| Abstract: | Targeting specific cell membrane markers for both diagnostic imaging and radionuclide therapy is a rapidly evolving field in cancer research. Some of these applications have now found a role in routine clinical practice and have been shown to have a significant impact on patient management. Several molecular targets are being investigated in ongoing clinical trials and show promise for future implementation. Advancements in molecular biology have facilitated the identification of new cancer-specific targets for radiopharmaceutical development. |
| URI: | https://bura.brunel.ac.uk/handle/2438/29417 |
| DOI: | https://doi.org/10.1016/j.nucmedbio.2020.06.005 |
| ISSN: | 0969-8051 |
| Other Identifiers: | ORCiD: Luigi Aloj https://orcid.org/0000-0002-7452-4961 ORCiD: Ai Hui Doreen Lau https://orcid.org/0000-0002-7623-2401 ORCiD: Laura Lechermann https://orcid.org/0000-0002-2742-6269 ORCiD: Evis Sala https://orcid.org/0000-0002-5518-9360 ORCiD: Fiona Gilbert https://orcid.org/0000-0002-0124-9962 ORCiD: Ferdia Gallagher https://orcid.org/0000-0003-4784-5230 |
| Appears in Collections: | Dept of Life Sciences Research Papers |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| FullText.pdf | Copyright © 2020 Elsevier. All rights reserved. This manuscript version is made available under the Creative Commons (CC-BY-NC-ND 4.0) Attribution-NonCommercial-NoDerivatives 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/), see: https://www.elsevier.com/about/policies/sharing. | 768.21 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License
