Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/32150
Title: AMSTAR-PF: a critical appraisal tool for systematic reviews of prognostic factor studies
Authors: Henry, ML
O'Connell, NE
Riley, RD
Moons, KGM
Shea, BJ
Hooft, L
Damen, JAA
Skoetz, N
Wallwork, SB
Moseley, LG
Issue Date: 22-Dec-2025
Publisher: BMJ Publishing Group
Citation: Henry, M.L. et al. (2025) 'AMSTAR-PF: a critical appraisal tool for systematic reviews of prognostic factor studies', BMJ: British Medical Journal, 391, e085718, pp. 1 - 11. doi: 10.1136/bmj-2025-085718.
Abstract: The ability to predict the onset or natural history of an illness, or how people may respond to a treatment, guides clinical decision making. These predictions are commonly based on prognostic factors: clinical, patient, or societal variables that are identified as being predictive of a certain future outcome. Prognostic factor research has increased across fields, with a subsequent increase in the number of systematic reviews of prognostic factors studies. Understanding the quality of such prognostic factor reviews is essential for confidence in their findings, but there is no quality appraisal instrument to specifically assess systematic reviews of prognostic factor studies. A MeaSurement Tool to Assess systematic Reviews of Prognostic Factor studies, AMSTAR-PF, has been developed to fill this gap.
Description: Data availability statement: Data related to agreement testing can be found in the referenced paper, or on reasonable request from the corresponding author at neil.oconnell@brunel.ac.uk. The draft versions of the tool and guidance notes generated during the development process are available on reasonable request, from the corresponding author.
A preprint version of the article is available at medRxiv, https://www.medrxiv.org/content/10.1101/2025.04.10.25325555v1 . It has not been certified by peer review. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
URI: https://bura.brunel.ac.uk/handle/2438/32150
DOI: https://doi.org/10.1136/bmj-2025-085718
ISSN: 1759-2151
Other Identifiers: ORCiD: Michael L. Henry https://orcid.org/0000-0003-2871-6695
ORCiD: Neil O'Connell https://orcid.org/0000-0003-1989-4537
ORCiD: Richard D. Riley https://orcid.org/0000-0001-8699-0735
ORCiD: Karel G. M. Moons https://orcid.org/0000-0003-2118-004X
ORCiD: Lotty Hooft https://orcid.org/0000-0002-7950-2980
ORCiD: Johanna A. A. Damen https://orcid.org/0000-0001-7401-4593
ORCiD: Nicole Skoetz https://orcid.org/0000-0003-4744-6192
Article number: e085718
Appears in Collections:Dept of Health Sciences Research Papers

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